› 3zrd

X-ray diffraction
1.74Å resolution

Function and Biology Details

Reaction catalysed: 
Thioredoxin + ROOH = thioredoxin disulfide + H(2)O + ROH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101804 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thiol peroxidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 200 amino acids
Theoretical weight: 21.4 KDa
Source organism: Yersinia pseudotuberculosis YPIII
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0H3B2F9 (Residues: 1-167; Coverage: 100%)
Gene names: YPK_1903, tpx
Sequence domains: Redoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 56.18Å b: 62.56Å c: 88Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.231
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Chemical inhibitors of the type three secretion system: disarming bacterial pathogens.
Duncan et al. (2012)
4 more

2 mentions without citation

Peroxiredoxins wear many hats: Factors that fashion their peroxide sensing personalities.
Bolduc et al. (2021)
1 more