› 3zw5

X-ray diffraction
1.6Å resolution

Crystal structure of the human Glyoxalase domain-containing protein 5

Released:
DOI: 10.2210/pdb3zw5/pdb
PDB entry 3zw5 coloured by chain, front view.
PDB entry 3zw5 coloured by chain, side view.
PDB entry 3zw5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Muniz JRC, Kiyani W, Froese S, Vollmar M, von Delft F, Burgess-Brown N, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Yue WW

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108002 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glyoxalase domain-containing protein 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 147 amino acids
Theoretical weight: 16.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A6NK44 (Residues: 34-157; Coverage: 78%)
Gene name: GLOD5
Sequence domains: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Structure domains: 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Ligands and Environments

3 bound ligands:
Ligand SO4 2 x SO4
Ligand PEG 1 x PEG
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 51.49Å b: 66.04Å c: 76.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.172 0.199
Expression system: Escherichia coli BL21(DE3)

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