› 481d

X-ray diffraction
1.6Å resolution

CRYSTAL STRUCTURE OF A HEXITOL NUCLEIC ACID (HNA) DUPLEX AT 1.6A RESOLUTION

Released:
DOI: 10.2210/pdb481d/pdb
PDB entry 481d coloured by chain, front view.
PDB entry 481d coloured by chain, side view.
PDB entry 481d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of double helical hexitol nucleic acids.
Declercq R, Van Aerschot A, Read RJ, Herdewijn P, Van Meervelt L
J Am Chem Soc 124 928-33 (2002)
PMID: 11829600

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117176 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-H(*(6HG)P*(6HT)P*(6HG)P*(6HT)P*(6HA)P*(6HC)P*(6HA)P*(6HC))-3' Chain: A
Molecule details ›
Chain: A
Length: 8 nucleotides
Theoretical weight: 2.54 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
4 modified residues:
Ligand 6HG 2 x 6HG
Ligand 6HT 2 x 6HT
Ligand 6HA 2 x 6HA
Ligand 6HC 2 x 6HC

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P3212
Unit cell:
a: 33.041Å b: 33.041Å c: 38.924Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.184 not available 0.229
Expression system: Not provided

Quick links

Citations

15 review citations

Synthetic biology.
Benner et al. (2005)
14 more

3 mentions without citation

The structural diversity of artificial genetic polymers.
Anosova et al. (2016)
2 more