› 4a1h

X-ray diffraction
2.2Å resolution

Human myelin P2 protein, K45S mutant

Released:
DOI: 10.2210/pdb4a1h/pdb
PDB entry 4a1h coloured by chain, front view.
PDB entry 4a1h coloured by chain, side view.
PDB entry 4a1h coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lehtimaki M, Kursula P

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136047 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myelin P2 protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 133 amino acids
Theoretical weight: 14.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P02689 (Residues: 1-132; Coverage: 100%)
Gene name: PMP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

3 bound ligands:
Ligand PLM 3 x PLM
Ligand GOL 1 x GOL
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: C2
Unit cell:
a: 120.13Å b: 63.61Å c: 84.47Å
α: 90° β: 130.1° γ: 90°
R-values:
R R work R free
0.197 0.194 0.252
Expression system: Escherichia coli BL21(DE3)

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