› 4a27

X-ray diffraction
2.1Å resolution

Crystal structure of human synaptic vesicle membrane protein VAT-1 homolog-like protein

Released:
DOI: 10.2210/pdb4a27/pdb
PDB entry 4a27 coloured by chain, front view.
PDB entry 4a27 coloured by chain, side view.
PDB entry 4a27 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vollmar M, Shafqat N, Muniz JRC, Krojer T, Allerston C, von Delft F, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, Yue WW, Oppermann U

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190779 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptic vesicle membrane protein VAT-1 homolog-like Chains: A, B
Molecule details ›
Chains: A, B
Length: 349 amino acids
Theoretical weight: 38.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HCJ6 (Residues: 41-387; Coverage: 83%)
Gene names: KIAA1576, VAT1L
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand EDO 9 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P21
Unit cell:
a: 69.509Å b: 62.104Å c: 83.795Å
α: 90° β: 106.98° γ: 90°
R-values:
R R work R free
0.187 0.185 0.23
Expression system: Escherichia coli BL21(DE3)

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