› 4a2u

X-ray diffraction
2.63Å resolution

CRP(CAP) from Myco. Tuberculosis, with cAMP

Released:
DOI: 10.2210/pdb4a2u/pdb
PDB entry 4a2u coloured by chain, front view.
PDB entry 4a2u coloured by chain, side view.
PDB entry 4a2u coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Entry authors: Gallagher DT, Reddy PT

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164269 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/ FNR-FAMILY) Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 227 amino acids
Theoretical weight: 25.11 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CMP 8 x CMP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P1
Unit cell:
a: 67.328Å b: 67.801Å c: 104.877Å
α: 84.41° β: 83.46° γ: 80.14°
R-values:
R R work R free
0.189 0.183 0.288
Expression system: Escherichia coli BL21(DE3)

Quick links