› 4a8z

X-ray diffraction
1.8Å resolution

Human myelin P2 protein, K112Q mutant

Released:
DOI: 10.2210/pdb4a8z/pdb
PDB entry 4a8z coloured by chain, front view.
PDB entry 4a8z coloured by chain, side view.
PDB entry 4a8z coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lehtimaki M, Ruskamo S, Kursula P

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136048 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myelin P2 protein Chain: A
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 14.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P02689 (Residues: 1-132; Coverage: 100%)
Gene name: PMP2
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

3 bound ligands:
Ligand PLM 1 x PLM
Ligand GOL 3 x GOL
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: P41212
Unit cell:
a: 65.71Å b: 65.71Å c: 101.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.178 0.203
Expression system: Escherichia coli BL21(DE3)

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