› 4abm

X-ray diffraction
1.8Å resolution

Crystal Structure of CHMP4B hairpin

Released:
DOI: 10.2210/pdb4abm/pdb
PDB entry 4abm coloured by chain, front view.
PDB entry 4abm coloured by chain, side view.
PDB entry 4abm coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
CC2D1A is a regulator of ESCRT-III CHMP4B.
Martinelli N, Hartlieb B, Usami Y, Sabin C, Dordor A, Miguet N, Avilov SV, Ribeiro EA, Göttlinger H, Weissenhorn W
J Mol Biol 419 75-88 (2012)
PMID: 22406677

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190596 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Charged multivesicular body protein 4b Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 79 amino acids
Theoretical weight: 9.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H444 (Residues: 23-97; Coverage: 34%)
Gene names: C20orf178, CHMP4B, SHAX1
Sequence domains: Snf7
Structure domains: ESAT-6-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 37.59Å b: 71.43Å c: 123.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.228 0.285
Expression system: Escherichia coli

Quick links

Citations

10 review citations

The many functions of ESCRTs.
Vietri et al. (2020)
9 more

6 mentions without citation

The ESCRT machinery: from the plasma membrane to endosomes and back again.
Schuh et al. (2014)
5 more