› 4adj

X-ray diffraction
1.94Å resolution

Crystal structure of the Rubella virus glycoprotein E1 in its post-fusion form crystallized in presence of 1mM of calcium acetate

Released:
DOI: 10.2210/pdb4adj/pdb
PDB entry 4adj coloured by chain, front view.
PDB entry 4adj coloured by chain, side view.
PDB entry 4adj coloured by chain, top view.
Source organism: Rubella virus
Primary publication:
Functional and evolutionary insight from the crystal structure of rubella virus protein E1.
DuBois RM, Vaney MC, Tortorici MA, Kurdi RA, Barba-Spaeth G, Krey T, Rey FA
Nature 493 552-6 (2013)
PMID: 23292515

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140178 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spike glycoprotein E1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 473 amino acids
Theoretical weight: 50.57 KDa
Source organism: Rubella virus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P08563 (Residues: 583-1018; Coverage: 41%)
Sequence domains: Rubella membrane glycoprotein E1
Structure domains:

Ligands and Environments

5 bound ligands:
Ligand NAG 4 x NAG
Ligand GOL 4 x GOL
Ligand NA 2 x NA
Ligand CA 3 x CA
Ligand ACT 4 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 121.875Å b: 126.899Å c: 130.946Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.182 0.194
Expression system: Drosophila melanogaster

Quick links

Citations

16 review citations

Viral membrane fusion.
Harrison SC. (2015)
15 more

5 mentions without citation

Recent Advances in Bunyavirus Glycoprotein Research: Precursor Processing, Receptor Binding and Structure.
Hulswit et al. (2021)
4 more