› 4ae3

X-ray diffraction
2.5Å resolution

Crystal structure of ammosamide 272:myosin-2 motor domain complex

Released:
DOI: 10.2210/pdb4ae3/pdb
PDB entry 4ae3 coloured by chain, front view.
PDB entry 4ae3 coloured by chain, side view.
PDB entry 4ae3 coloured by chain, top view.
Source organism: Dictyostelium discoideum AX4
Entry authors: Chinthalapudi K, Heissler SM, Fenical W, Manstein DJ

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myosin-2 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 776 amino acids
Theoretical weight: 88.51 KDa
Source organism: Dictyostelium discoideum AX4
Expression system: Dictyostelium discoideum AX4
UniProt:
  • Canonical: P08799 (Residues: 2-761; Coverage: 36%)
Gene names: DDB_G0286355, mhcA
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand AOV 1 x AOV
Ligand MG 1 x MG
Ligand 27X 2 x 27X
Ligand EDO 4 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER X8 PROTEUM
Spacegroup: C2221
Unit cell:
a: 88.05Å b: 145.52Å c: 153.83Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.214 0.254
Expression system: Dictyostelium discoideum AX4

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