› 4aiq

X-ray diffraction
2.6Å resolution

The FrpB iron transporter from Neisseria meningitidis (F5-1 variant)

Released:
DOI: 10.2210/pdb4aiq/pdb
PDB entry 4aiq coloured by chain, front view.
PDB entry 4aiq coloured by chain, side view.
PDB entry 4aiq coloured by chain, top view.
Source organism: Neisseria meningitidis
Primary publication:
Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis.
Saleem M, Prince SM, Rigby SE, Imran M, Patel H, Chan H, Sanders H, Maiden MC, Feavers IM, Derrick JP
PLoS One 8 e56746 (2013)
PMID: 23457610

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164280 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
FERRIC ENTEROBACTIN RECEPTOR Chain: A
Molecule details ›
Chain: A
Length: 745 amino acids
Theoretical weight: 82.71 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand FE 1 x FE
Ligand IMD 1 x IMD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: C2
Unit cell:
a: 175.98Å b: 78.69Å c: 73.43Å
α: 90° β: 97.22° γ: 90°
R-values:
R R work R free
0.229 0.227 0.277
Expression system: Escherichia coli

Quick links

Citations

2 review citations

How the Knowledge of Interactions between Meningococcus and the Human Immune System Has Been Used to Prepare Effective Neisseria meningitidis Vaccines.
Gasparini et al. (2015)
1 more

4 mentions without citation

Structural Basis for Evasion of Nutritional Immunity by the Pathogenic Neisseriae.
Yadav et al. (2019)
3 more