› 4ajv

X-ray diffraction
2.7Å resolution

Structure of mouse ZP-C domain of TGF-Beta-Receptor-3

Released:
DOI: 10.2210/pdb4ajv/pdb
PDB entry 4ajv coloured by chain, front view.
PDB entry 4ajv coloured by chain, side view.
PDB entry 4ajv coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3).
Diestel U, Resch M, Meinhardt K, Weiler S, Hellmann TV, Mueller TD, Nickel J, Eichler J, Muller YA
PLoS One 8 e67214 (2013)
PMID: 23826237

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131536 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transforming growth factor beta receptor type 3 Chain: A
Molecule details ›
Chain: A
Length: 167 amino acids
Theoretical weight: 19.02 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: O88393 (Residues: 591-757; Coverage: 20%)
Gene name: Tgfbr3
Sequence domains: Zona pellucida-like domain
Structure domains: Zona pellucida, ZP-C domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 49.66Å b: 56.82Å c: 60.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.22 0.296
Expression system: Homo sapiens

Quick links

Citations

11 review citations

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans.
Iozzo et al. (2015)
10 more

2 mentions without citation

Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family.
Kim et al. (2019)
1 more