› 4ak4

X-ray diffraction
1.65Å resolution

High resolution structure of Galactose Binding lectin from Champedak (CGB)

Released:
DOI: 10.2210/pdb4ak4/pdb
PDB entry 4ak4 coloured by chain, front view.
PDB entry 4ak4 coloured by chain, side view.
PDB entry 4ak4 coloured by chain, top view.
Source organism: Artocarpus integer
Primary publication:
Structures and binding specificity of galactose- and mannose-binding lectins from champedak: differences from jackfruit lectins.
Gabrielsen M, Abdul-Rahman PS, Othman S, Hashim OH, Cogdell RJ
Acta Crystallogr F Struct Biol Commun 70 709-16 (2014)
PMID: 24915077

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148430 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Agglutinin alpha chain Chains: A, C, E, G, I, K, M, O
Molecule details ›
Chains: A, C, E, G, I, K, M, O
Length: 133 amino acids
Theoretical weight: 14.69 KDa
Source organism: Artocarpus integer
UniProt:
  • Canonical: P18670 (Residues: 1-133; Coverage: 100%)
Sequence domains: Jacalin-like lectin domain
Structure domains: Jacalin-like lectin domain
Agglutinin beta-4 chain Chains: B, D, F, H, J, L, N, P
Molecule details ›
Chains: B, D, F, H, J, L, N, P
Length: 21 amino acids
Theoretical weight: 2.16 KDa
Source organism: Artocarpus integer
UniProt:
  • Canonical: Q9S8T0 (Residues: 1-19; Coverage: 95%)

Ligands and Environments

1 bound ligand:
Ligand P6G 6 x P6G
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P21
Unit cell:
a: 76.171Å b: 121.729Å c: 77.736Å
α: 90° β: 90.61° γ: 90°
R-values:
R R work R free
0.166 0.165 0.19

Quick links

Citations

1 review citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)
5 other articles

8 mentions without citation

Classification of a Hypervirulent Aeromonas hydrophila Pathotype Responsible for Epidemic Outbreaks in Warm-Water Fishes.
Rasmussen-Ivey et al. (2016)
7 more