Function and Biology Details
Reaction catalysed:
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- P-loop containing nucleoside triphosphate hydrolase
- AAA+ ATPase domain
- Glutathione S-transferase, N-terminal
- Dynein heavy chain AAA lid domain
- Dynein heavy chain AAA lid domain superfamily
- Dynein heavy chain region D6 P-loop domain
- Dynein heavy chain, ATP-binding dynein motor region
- Dynein heavy chain
11 more domains
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140155 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dynein heavy chain, cytoplasmic; Glutathione S-transferase class-mu 26 kDa isozyme
Molecule details ›
Chains: A, B
Length: 2695 amino acids
Theoretical weight: 310.21 KDa
Source organisms: Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 2695 amino acids
Theoretical weight: 310.21 KDa
Source organisms: Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
P08515 (Residues: 2-218; Coverage: 100%) - Canonical: P36022 (Residues: 1364-4092; Coverage: 61%)
Sequence domains:
- Glutathione S-transferase, N-terminal domain
- Glutathione S-transferase, C-terminal domain
- Dynein heavy chain, N-terminal region 2
- Hydrolytic ATP binding site of dynein motor region
- DYN1, AAA+ ATPase lid domain
- P-loop containing dynein motor region
- AAA+ lid domain
- P-loop containing dynein motor region D4
- Microtubule-binding stalk of dynein motor
- ATP-binding dynein motor region
- Dynein heavy chain region D6 P-loop domain
- Dynein heavy chain AAA lid domain
- Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
- Dynein heavy chain, N-terminal domain 2
- Dynein heavy chain, N-terminal domain 2
- Methane Monooxygenase Hydroxylase; Chain G, domain 1
- P-loop containing nucleotide triphosphate hydrolases
- Helicase, Ruva Protein; domain 3
- Cyclin A; domain 1
- Histone Acetyltransferase; Chain A
- Histone Acetyltransferase; Chain A
- Helicase, Ruva Protein; domain 3
- Monooxygenase
- Region D6 of dynein motor
