› 4apl

X-ray diffraction
2.9Å resolution

Crystal Structure of AMA1 from Neospora caninum

Released:
DOI: 10.2210/pdb4apl/pdb
PDB entry 4apl coloured by chain, front view.
PDB entry 4apl coloured by chain, side view.
PDB entry 4apl coloured by chain, top view.
Source organism: Neospora caninum
Primary publication:
Babesia divergens and Neospora caninum apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion.
Tonkin ML, Crawford J, Lebrun ML, Boulanger MJ
Protein Sci 22 114-27 (2013)
PMID: 23169033

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106801 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apical membrane antigen 1 Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 431 amino acids
Theoretical weight: 47.99 KDa
Source organism: Neospora caninum
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A2A114 (Residues: 59-478; Coverage: 75%)
Gene name: AMA1
Sequence domains: Apical membrane antigen 1
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2
Unit cell:
a: 251.56Å b: 51Å c: 145.34Å
α: 90° β: 90.93° γ: 90°
R-values:
R R work R free
0.197 0.193 0.271
Expression system: Trichoplusia ni

Quick links

Citations

2 review citations

Vaccines against neosporosis: what can we learn from the past studies?
Monney et al. (2014)
1 more

2 mentions without citation

The apicomplexan glideosome and adhesins - Structures and function.
Boucher et al. (2015)
1 more