4aps

X-ray diffraction
3.3Å resolution

Crystal structure of a POT family peptide transporter in an inward open conformation.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-177588 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major facilitator superfamily (MFS) profile domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 491 amino acids
Theoretical weight: 53.72 KDa
Source organism: Streptococcus thermophilus LMG 18311
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5M4H8 (Residues: 1-483; Coverage: 100%)
Gene names: dtpT, stu0970
Sequence domains: POT family
Structure domains: MFS general substrate transporter like domains

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 89.39Å b: 112.99Å c: 215.49Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.273 0.272 0.29
Expression system: Escherichia coli BL21(DE3)