› 4aqs

X-ray diffraction
3.11Å resolution

Laminin beta1 LN-LE1-4 structure

Released:
DOI: 10.2210/pdb4aqs/pdb
PDB entry 4aqs coloured by chain, front view.
PDB entry 4aqs coloured by chain, side view.
PDB entry 4aqs coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structures of the network-forming short-arm tips of the laminin β1 and γ1 chains.
Carafoli F, Hussain SA, Hohenester E
PLoS One 7 e42473 (2012)
PMID: 22860131

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135870 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Laminin subunit beta-1 Chain: A
Molecule details ›
Chain: A
Length: 525 amino acids
Theoretical weight: 58.7 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P02469 (Residues: 22-542; Coverage: 30%)
Gene names: Lamb-1, Lamb1, Lamb1-1
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, FUL
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2221
Unit cell:
a: 143.99Å b: 152.95Å c: 92.985Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.246 0.246 0.287
Expression system: Homo sapiens

Quick links

Citations

7 review citations

The laminin family.
Aumailley M. (2013)
6 more

16 mentions without citation

Laminin 332 processing impacts cellular behavior.
Rousselle et al. (2013)
15 more