› 4aqt

X-ray diffraction
3.2Å resolution

Laminin gamma1 LN-LE1-2 structure

Released:
DOI: 10.2210/pdb4aqt/pdb
PDB entry 4aqt coloured by chain, front view.
PDB entry 4aqt coloured by chain, side view.
PDB entry 4aqt coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structures of the network-forming short-arm tips of the laminin β1 and γ1 chains.
Carafoli F, Hussain SA, Hohenester E
PLoS One 7 e42473 (2012)
PMID: 22860131

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135868 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Laminin subunit gamma-1 Chain: A
Molecule details ›
Chain: A
Length: 375 amino acids
Theoretical weight: 41.98 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P02468 (Residues: 33-395; Coverage: 23%)
Gene names: Lamb-2, Lamc-1, Lamc1
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
2 bound ligands:
Ligand CA 1 x CA
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: R32
Unit cell:
a: 203.01Å b: 203.01Å c: 93.69Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.231 0.275
Expression system: Homo sapiens

Quick links

Citations

9 review citations

The laminin family.
Aumailley M. (2013)
8 more

8 mentions without citation

Structural biology of laminins.
Hohenester E. (2019)
7 more