› 4au4

X-ray diffraction
2.97Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111677 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serpin H1 Chains: A, B, C, D, E, F, G
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 392 amino acids
Theoretical weight: 44.28 KDa
Source organism: Canis lupus familiaris
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: C7C419 (Residues: 36-418; Coverage: 96%)
Gene name: SERPINH1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: C2
Unit cell:
a: 178.78Å b: 115.11Å c: 188.275Å
α: 90° β: 107.69° γ: 90°
R-values:
R R work R free
0.182 0.18 0.22
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

14 review citations

Bone collagen: new clues to its mineralization mechanism from recessive osteogenesis imperfecta.
Eyre et al. (2013)
13 more

2 mentions without citation

Molecular basis for the action of the collagen-specific chaperone Hsp47/SERPINH1 and its structure-specific client recognition.
Widmer et al. (2012)
1 more