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› 4au6

Electron Microscopy
6Å resolution

Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles

Released:
DOI: 10.2210/pdb4au6/pdb
PDB entry 4au6 coloured by chain, front view.
PDB entry 4au6 coloured by chain, side view.
PDB entry 4au6 coloured by chain, top view.
Source organism: Bovine rotavirus
Primary publication:
Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles.
Estrozi LF, Settembre EC, Goret G, McClain B, Zhang X, Chen JZ, Grigorieff N, Harrison SC
J Mol Biol 425 124-32 (2013)
PMID: 23089332
Related structures: EMD-2100

Function and Biology Details

Reaction catalysed: 
RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109867 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RNA-directed RNA polymerase Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 1095 amino acids
Theoretical weight: 126.32 KDa
Source organism: Bovine rotavirus
Expression system: Not provided
UniProt:
  • Canonical: B3IWN8 (Residues: 1-1088; Coverage: 100%)
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 6Å
Relevant EMDB volumes: EMD-2100
Expression system: Not provided

Quick links

Citations

9 review citations

Taxonomic reorganization of family Partitiviridae and other recent progress in partitivirus research.
Nibert et al. (2014)
8 more

4 mentions without citation

Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles.
Estrozi et al. (2013)
3 more