Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
E3 ubiquitin-protein ligase RNF8 (preferred)
PDBe Complex ID:
PDB-CPX-131200 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
E3 ubiquitin-protein ligase RNF8
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 16.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains:
Length: 138 amino acids
Theoretical weight: 16.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
O76064 (Residues: 351-485; Coverage: 28%)
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains:
E3 ubiquitin-protein ligase RNF8
Molecule details ›
Chain: B
Length: 138 amino acids
Theoretical weight: 16.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
Length: 138 amino acids
Theoretical weight: 16.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: O76064 (Residues: 351-485; Coverage: 28%)
Sequence domains: Zinc finger, C3HC4 type (RING finger)
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
