› 4b7o

X-ray diffraction
2.32Å resolution

THE FrpB IRON TRANSPORTER FROM NEISSERIA MENINGITIDIS (F5-1 VARIANT) APOPROTEIN FORM

Released:
DOI: 10.2210/pdb4b7o/pdb
PDB entry 4b7o coloured by chain, front view.
PDB entry 4b7o coloured by chain, side view.
PDB entry 4b7o coloured by chain, top view.
Source organism: Neisseria meningitidis
Primary publication:
Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis.
Saleem M, Prince SM, Rigby SE, Imran M, Patel H, Chan H, Sanders H, Maiden MC, Feavers IM, Derrick JP
PLoS One 8 e56746 (2013)
PMID: 23457610

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182988 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Iron-regulated outer membrane protein Chain: A
Molecule details ›
Chain: A
Length: 745 amino acids
Theoretical weight: 82.71 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli B
UniProt:
  • Canonical: Q841A2 (Residues: 1-672; Coverage: 100%)
Gene name: fetA
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: C2
Unit cell:
a: 175.21Å b: 79.1Å c: 74.75Å
α: 90° β: 97.58° γ: 90°
R-values:
R R work R free
0.236 0.233 0.281
Expression system: Escherichia coli B

Quick links

Citations

3 review citations

Structural Basis for Evasion of Nutritional Immunity by the Pathogenic Neisseriae.
Yadav et al. (2019)
2 more

2 mentions without citation

Use of a molecular decoy to segregate transport from antigenicity in the FrpB iron transporter from Neisseria meningitidis.
Saleem et al. (2013)
1 more