Function and Biology Details
Reaction catalysed:
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Signal transduction histidine kinase-related protein, C-terminal
- Signal transduction histidine kinase, dimerisation/phosphoacceptor domain
- Histidine kinase/HSP90-like ATPase
- Histidine kinase/HSP90-like ATPase superfamily
- HAMP domain
- Histidine kinase domain
- Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Sensor histidine kinase CpxA (preferred)
PDBe Complex ID:
PDB-CPX-142416 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sensor histidine kinase CpxA
Molecule details ›
Chains: A, B
Length: 298 amino acids
Theoretical weight: 33.72 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 298 amino acids
Theoretical weight: 33.72 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical:
P0AE82 (Residues: 188-457; Coverage: 59%)
Sequence domains:
- HAMP domain
- His Kinase A (phospho-acceptor) domain
- Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
