› 4bl6

X-ray diffraction
2.18Å resolution

Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein

Released:
DOI: 10.2210/pdb4bl6/pdb
Model geometry
Fit model/data
PDB entry 4bl6 coloured by chain, front view.
PDB entry 4bl6 coloured by chain, side view.
PDB entry 4bl6 coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein.
Liu Y, Salter HK, Holding AN, Johnson CM, Stephens E, Lukavsky PJ, Walshaw J, Bullock SL
Genes Dev 27 1233-46 (2013)
PMID: 23723415

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147768 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein bicaudal D Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 94 amino acids
Theoretical weight: 11.26 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: P16568 (Residues: 656-745; Coverage: 12%)
Gene names: BicD, CG6605
Sequence domains: Microtubule-associated protein Bicaudal-D
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

1 bound ligand:
Ligand ARG 1 x ARG
1 modified residue:
Ligand MSE 20 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P61
Unit cell:
a: 62.199Å b: 62.199Å c: 190.511Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.204 0.235
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Coiled-coils: The long and short of it.
Truebestein et al. (2016)
9 more

7 mentions without citation

mRNA localization in metazoans: A structural perspective.
Lazzaretti et al. (2017)
6 more