4bl9

X-ray diffraction
2.8Å resolution

Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form I)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-238711 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Maltose/maltodextrin-binding periplasmic protein; Suppressor of fused homolog Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 756 amino acids
Theoretical weight: 84.05 KDa
Source organisms: Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0AEX9 (Residues: 27-393; Coverage: 99%)
  • Canonical: Q9UMX1 (Residues: 32-278, 361-483; Coverage: 76%)
Gene names: JW3994, SUFU, UNQ650/PRO1280, b4034, malE
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P1
Unit cell:
a: 93.43Å b: 103.28Å c: 111.51Å
α: 63.67° β: 81.13° γ: 76.03°
R-values:
R R work R free
0.201 0.2 0.234
Expression system: Escherichia coli BL21(DE3)