› 4bw8

X-ray diffraction
1.8Å resolution

Calmodulin with small bend in central helix

Released:
DOI: 10.2210/pdb4bw8/pdb
PDB entry 4bw8 coloured by chain, front view.
PDB entry 4bw8 coloured by chain, side view.
PDB entry 4bw8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallographic snapshots of initial steps in the collapse of the calmodulin central helix.
Kursula P
Acta Crystallogr D Biol Crystallogr 70 24-30 (2014)
PMID: 24419375

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143908 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DP23 (Residues: 1-149; Coverage: 100%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair

Ligands and Environments

1 bound ligand:
Ligand CA 8 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-2
Spacegroup: P1
Unit cell:
a: 24.38Å b: 53.85Å c: 59.36Å
α: 88.52° β: 83.02° γ: 86.37°
R-values:
R R work R free
0.238 0.236 0.278
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

The many structural faces of calmodulin: a multitasking molecular jackknife.
Kursula P. (2014)
4 other articles

5 mentions without citation

Defining potential roles of Pb(2+) in neurotoxicity from a calciomics approach.
Gorkhali et al. (2016)
4 more