› 4c64

X-ray diffraction
1.32Å resolution

ULTRA HIGH RESOLUTION DICKERSON-DREW DODECAMER B-DNA

Released:
DOI: 10.2210/pdb4c64/pdb
PDB entry 4c64 coloured by chain, front view.
PDB entry 4c64 coloured by chain, side view.
PDB entry 4c64 coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Structural insights into how 5-hydroxymethylation influences transcription factor binding.
Lercher L, McDonough MA, El-Sagheer AH, Thalhammer A, Kriaucionis S, Brown T, Schofield CJ
Chem Commun (Camb) 50 1794-6 (2014)
PMID: 24287551

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117279 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*GP)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.66 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P212121
Unit cell:
a: 25.149Å b: 39.84Å c: 65.598Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.143 0.138 0.182
Expression system: Not provided

Quick links

Citations

6 review citations

TET proteins in natural and induced differentiation.
Scott-Browne et al. (2017)
5 more

16 mentions without citation

Beyond the double helix: DNA structural diversity and the PDB.
Neidle S. (2021)
15 more