4c7r

X-ray diffraction
2.7Å resolution

Inward facing conformation of the trimeric betaine transporter BetP in complex with lipids

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
PDBe Complex ID:
PDB-CPX-157051 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycine betaine transporter BetP Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 566 amino acids
Theoretical weight: 61 KDa
Source organism: Corynebacterium glutamicum
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P54582 (Residues: 30-595; Coverage: 95%)
Gene names: Cgl0892, betP, cg1016
Sequence domains: BCCT, betaine/carnitine/choline family transporter
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 115.56Å b: 129.5Å c: 167.95Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.212 0.266
Expression system: Escherichia coli BL21