› 4chw

Electron crystallography
7Å resolution

The electron crystallography structure of the cAMP-free potassium channel MloK1

Released:
DOI: 10.2210/pdb4chw/pdb
PDB entry 4chw coloured by chain, front view.
PDB entry 4chw coloured by chain, side view.
PDB entry 4chw coloured by chain, top view.
Source organism: Mesorhizobium loti
Primary publication:
Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Kowal J, Chami M, Baumgartner P, Arheit M, Chiu PL, Rangl M, Scheuring S, Schröder GF, Nimigean CM, Stahlberg H
Nat Commun 5 3106 (2014)
PMID: 24469021
Related structures: EMD-2527

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189151 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclic nucleotide-gated potassium channel mll3241 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 361 amino acids
Theoretical weight: 38.6 KDa
Source organism: Mesorhizobium loti
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q98GN8 (Residues: 1-355; Coverage: 100%)
Gene name: mll3241
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand K 2 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 7Å
Relevant EMDB volumes: EMD-2527
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Structural insights into the mechanisms of CNBD channel function.
James et al. (2018)
6 more

3 mentions without citation

Durable vesicles for reconstitution of membrane proteins in biotechnology.
Beales et al. (2017)
2 more