› 4cpd

X-ray diffraction
2.74Å resolution

Function and Biology Details

Reaction catalysed: 
A primary alcohol + NAD(+) = an aldehyde + NADH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109781 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enoyl reductase (ER) domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 347 amino acids
Theoretical weight: 37.23 KDa
Source organism: Thermus sp. ATN1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B2ZRE3 (Residues: 1-347; Coverage: 100%)
Gene name: tadh
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 3 x NAD
1 bound ligand:
Ligand ZN 8 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P3121
Unit cell:
a: 87.367Å b: 87.367Å c: 337.56Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.192 0.248
Expression system: Escherichia coli BL21(DE3)

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