› 4cur

X-ray diffraction
1.84Å resolution

Crystal structure of human BAZ2B in complex with fragment-3 N09555

Released:
DOI: 10.2210/pdb4cur/pdb
PDB entry 4cur coloured by chain, front view.
PDB entry 4cur coloured by chain, side view.
PDB entry 4cur coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Bradley AR, Liu Y, Krojer T, Bountra C, Arrowsmith CH, Edwards A, Knapp S, von Delft F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193784 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain adjacent to zinc finger domain protein 2B Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UIF8 (Residues: 2054-2168; Coverage: 5%)
Gene names: BAZ2B, KIAA1476
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

2 bound ligands:
Ligand EDO 1 x EDO
Ligand LA7 1 x LA7
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: C2221
Unit cell:
a: 81.1Å b: 96.6Å c: 57.93Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.202
Expression system: Escherichia coli BL21(DE3)

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