4czb

X-ray diffraction
3.5Å resolution

Structure of the sodium proton antiporter MjNhaP1 from Methanocaldococcus jannaschii at pH 8.

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
hetero dimer
PDBe Complex ID:
PDB-CPX-178773 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Na(+)/H(+) antiporter 1 Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 426 amino acids
Theoretical weight: 46 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q60362 (Residues: 1-426; Coverage: 100%)
Gene name: MJ0057
Sequence domains: Sodium/hydrogen exchanger family
Na(+)/H(+) antiporter 1 Chain: C
Molecule details ›
Chain: C
Length: 426 amino acids
Theoretical weight: 46.01 KDa
Source organism: Methanocaldococcus jannaschii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q60362 (Residues: 1-426; Coverage: 100%)
Gene name: MJ0057
Sequence domains: Sodium/hydrogen exchanger family

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 98.437Å b: 102.544Å c: 132.096Å
α: 90° β: 105.63° γ: 90°
R-values:
R R work R free
0.252 0.252 0.302
Expression system: Escherichia coli BL21(DE3)