› 4d2g

X-ray diffraction
2.65Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146058 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proliferating cell nuclear antigen Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 264 amino acids
Theoretical weight: 29.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
Structure domains: Proliferating Cell Nuclear Antigen
PCNA-associated factor Chains: D, E
Molecule details ›
Chains: D, E
Length: 21 amino acids
Theoretical weight: 2.31 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: Q15004 (Residues: 52-69; Coverage: 16%)
Gene names: KIAA0101, L5, NS5ATP9, PAF, PCLAF

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 76.053Å b: 41.228Å c: 141.121Å
α: 90° β: 105.39° γ: 90°
R-values:
R R work R free
0.174 0.17 0.25
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

4 review citations

Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.
Choe et al. (2017)
3 more

12 mentions without citation

Human PCNA Structure, Function and Interactions.
González-Magaña et al. (2020)
11 more