› 4d6k

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190504 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deoxynucleotidyltransferase terminal-interacting protein 1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 92 amino acids
Theoretical weight: 10.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H147 (Residues: 56-147; Coverage: 28%)
Gene names: C20orf167, DNTTIP1, TDIF1
Sequence domains: DNTTIP1 dimerisation domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 54.91Å b: 103.051Å c: 108.931Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.224
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy.
Li et al. (2020)
8 more

4 mentions without citation

Touch, act and go: landing and operating on nucleosomes.
Speranzini et al. (2016)
3 more