› 4d6w

X-ray diffraction
3.6Å resolution

Crystal Structure of the low pH conformation of Chandipura Virus glycoprotein G ectodomain

Released:
DOI: 10.2210/pdb4d6w/pdb
PDB entry 4d6w coloured by chain, front view.
PDB entry 4d6w coloured by chain, side view.
PDB entry 4d6w coloured by chain, top view.
Source organism: Chandipura virus
Primary publication:
Structure of the low pH conformation of Chandipura virus G reveals important features in the evolution of the vesiculovirus glycoprotein.
Baquero E, Albertini AA, Raux H, Buonocore L, Rose JK, Bressanelli S, Gaudin Y
PLoS Pathog 11 e1004756 (2015)
PMID: 25803715

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146491 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 419 amino acids
Theoretical weight: 46.81 KDa
Source organism: Chandipura virus
Expression system: Vesicular stomatitis virus
UniProt:
  • Canonical: P13180 (Residues: 22-440; Coverage: 82%)
Gene name: G
Sequence domains: Rhabdovirus spike glycoprotein
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 365.59Å b: 83.5Å c: 60.82Å
α: 90° β: 96.95° γ: 90°
R-values:
R R work R free
0.197 0.193 0.26
Expression system: Vesicular stomatitis virus

Quick links

Citations

3 review citations

Fusion of Enveloped Viruses in Endosomes.
White et al. (2016)
2 more

3 mentions without citation

Monomeric Intermediates Formed by Vesiculovirus Glycoprotein during Its Low-pH-induced Structural Transition.
Abou-Hamdan et al. (2018)
2 more