› 4dbd

X-ray diffraction
1.7Å resolution

Crystal structure of orotidine 5'-monophosphate decarboxylase from Sulfolobus solfataricus

Released:
DOI: 10.2210/pdb4dbd/pdb
PDB entry 4dbd coloured by chain, front view.
PDB entry 4dbd coloured by chain, side view.
PDB entry 4dbd coloured by chain, top view.
Source organism: Saccharolobus solfataricus 98/2
Entry authors: Fedorov AA, Fedorov EV, Desai B, Gerlt JA, Almo SC

Function and Biology Details

Reaction catalysed: 
Orotidine 5'-phosphate = UMP + CO(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Orotidine 5'-phosphate decarboxylase Chain: A
Molecule details ›
Chain: A
Length: 222 amino acids
Theoretical weight: 24.73 KDa
Source organism: Saccharolobus solfataricus 98/2
Expression system: Escherichia coli
UniProt:
  • Canonical: D0KT28 (Residues: 1-222; Coverage: 100%)
Gene names: Ssol_1680, pyrF
Sequence domains: Orotidine 5'-phosphate decarboxylase / HUMPS family
Structure domains: Aldolase class I

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P21212
Unit cell:
a: 40.367Å b: 64.819Å c: 73.237Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.208 0.245
Expression system: Escherichia coli

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