Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- SH2 domain
- Tyrosine-specific protein phosphatase, PTPase domain
- SH2 domain superfamily
- Protein-tyrosine phosphatase-like
- Protein-tyrosine phosphatase, active site
- Tyrosine-specific protein phosphatases domain
- Protein-tyrosine phosphatase, catalytic
- Protein-tyrosine phosphatase, non-receptor type-6, -11
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170287 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase non-receptor type 11
Molecule details ›
Chain: A
Length: 536 amino acids
Theoretical weight: 61.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 536 amino acids
Theoretical weight: 61.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q06124 (Residues: 1-528; Coverage: 89%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
APS BEAMLINE 19-BM
Spacegroup:
P21212
Expression system: Escherichia coli BL21(DE3)
