› 4diq

X-ray diffraction
2.4Å resolution

Crystal Structure of human NO66

Released:
DOI: 10.2210/pdb4diq/pdb
PDB entry 4diq coloured by chain, front view.
PDB entry 4diq coloured by chain, side view.
PDB entry 4diq coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vollmar M, Krojer T, Ng S, Pilka E, Bray J, Pike ACW, Filippakopoulos P, Roos A, Arrowsmith CH, Edwards E, Bountra C, von Delft F, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
(1a) a [histone H3]-N(6),N(6)-dimethyl-L-lysine(36) + 2-oxoglutarate + O(2) = a [histone H3]-N(6)-methyl-L-lysine(36) + succinate + formaldehyde + CO(2)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-190648 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosomal oxygenase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 489 amino acids
Theoretical weight: 55.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H6W3 (Residues: 167-641; Coverage: 74%)
Gene names: C14orf169, MAPJD, NO66, RIOX1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand NI 2 x NI
Ligand PD2 2 x PD2
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 78.674Å b: 149.55Å c: 105.311Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.185 0.23
Expression system: Escherichia coli

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