› 4dns

X-ray diffraction
2.15Å resolution

Crystal structure of Bermuda grass isoallergen BG60 provides insight into the various cross-allergenicity of the pollen group 4 allergens

Released:
DOI: 10.2210/pdb4dns/pdb
PDB entry 4dns coloured by chain, front view.
PDB entry 4dns coloured by chain, side view.
PDB entry 4dns coloured by chain, top view.
Source organism: Cynodon dactylon
Primary publication:
Various cross-reactivity of the grass pollen group 4 allergens: crystallographic study of the Bermuda grass isoallergen Cyn d 4.
Huang TH, Peng HJ, Su SN, Liaw SH
Acta Crystallogr D Biol Crystallogr 68 1303-10 (2012)
PMID: 22993084

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177760 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Berberine bridge enzyme-like Cyn d 4 Chains: A, B
Molecule details ›
Chains: A, B
Length: 497 amino acids
Theoretical weight: 54.92 KDa
Source organism: Cynodon dactylon
UniProt:
  • Canonical: Q5QJ60 (Residues: 26-522; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand FAD 2 x FAD
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6B
Spacegroup: P43212
Unit cell:
a: 86.043Å b: 86.043Å c: 309.432Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.18 0.22

Quick links

Citations

1 review citation

Grass pollen allergens globally: the contribution of subtropical grasses to burden of allergic respiratory diseases.
Davies JM. (2014)

2 mentions without citation

Structure of allergens and structure based epitope predictions.
Dall'antonia et al. (2014)
1 more