Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Leu is conserved at position P1 for all four cleavage sites. Alanine is found at position P1' of the NS4A-NS4B cleavage site, whereas serine is found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
(1a) RNA = an (RNA fragment)-3'-nucleoside-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA fragment)
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Non-structural protein 5A (preferred)
PDBe Complex ID:
PDB-CPX-188318 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
E(rns) glycoprotein
Molecule details ›
Chains: A, B
Length: 167 amino acids
Theoretical weight: 19.01 KDa
Source organism: Bovine viral diarrhea virus 1-CP7
Expression system: Drosophila melanogaster
UniProt:
Length: 167 amino acids
Theoretical weight: 19.01 KDa
Source organism: Bovine viral diarrhea virus 1-CP7
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
Q96662 (Residues: 271-435; Coverage: 4%)
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06SA
Spacegroup:
P21212
Expression system: Drosophila melanogaster
