› 4dz4

X-ray diffraction
1.7Å resolution

Function and Biology Details

Reaction catalysed: 
Agmatine + H(2)O = putrescine + urea
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174011 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Agmatinase, putative Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 324 amino acids
Theoretical weight: 34.84 KDa
Source organism: Burkholderia thailandensis E264
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2T3W4 (Residues: 1-320; Coverage: 100%)
Gene name: BTH_II1941
Sequence domains: Arginase family
Structure domains: Ureohydrolase domain

Ligands and Environments

3 bound ligands:
Ligand MN 12 x MN
Ligand EDO 47 x EDO
Ligand UNK 14 x UNK
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 99.08Å b: 101.25Å c: 102.99Å
α: 90° β: 97.09° γ: 90°
R-values:
R R work R free
0.154 0.152 0.175
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product.
Dailey et al. (2017)
10 more

5 mentions without citation

Combining functional and structural genomics to sample the essential Burkholderia structome.
Baugh et al. (2013)
4 more