› 4e1q

X-ray diffraction
1.25Å resolution

Crystal structure of Wheat Cyclophilin A at 1.25 A resolution

Released:
DOI: 10.2210/pdb4e1q/pdb
PDB entry 4e1q coloured by chain, front view.
PDB entry 4e1q coloured by chain, side view.
PDB entry 4e1q coloured by chain, top view.
Source organism: Triticum aestivum
Primary publication:
Structural and biochemical characterization of the cytosolic wheat cyclophilin TaCypA-1.
Sekhon SS, Kaur H, Dutta T, Singh K, Kumari S, Kang S, Park SG, Park BC, Jeong DG, Pareek A, Woo EJ, Singh P, Yoon TS
Acta Crystallogr D Biol Crystallogr 69 555-63 (2013)
PMID: 23519664

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188151 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 22.25 KDa
Source organism: Triticum aestivum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q93W25 (Residues: 1-171; Coverage: 100%)
Gene names: CFC21_082064, CFC21_091348, CFC21_091349, CyP1, CyP3, TaBWCyp A-1
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P212121
Unit cell:
a: 37.135Å b: 52.942Å c: 77.767Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.178 0.185
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Plant Cyclophilins: Multifaceted Proteins With Versatile Roles.
Singh et al. (2020)
1 more

3 mentions without citation

Characterization of Peptidyl-Prolyl Cis-Trans Isomerase- and Calmodulin-Binding Activity of a Cytosolic Arabidopsis thaliana Cyclophilin AtCyp19-3.
Kaur et al. (2015)
2 more