› 4e58

X-ray diffraction
1.95Å resolution

Crystal structure of GCC(LCG)CCGC duplex containing LNA residue

Released:
DOI: 10.2210/pdb4e58/pdb
PDB entry 4e58 coloured by chain, front view.
PDB entry 4e58 coloured by chain, side view.
PDB entry 4e58 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallographic characterization of CCG repeats.
Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W
Nucleic Acids Res 40 8155-62 (2012)
PMID: 22718980

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196793 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA duplex containing CCG repeats Chains: C, D, E
Molecule details ›
Chains: C, D, E
Length: 8 nucleotides
Theoretical weight: 2.53 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
1 modified residue:
Ligand LCG 3 x LCG

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P4322
Unit cell:
a: 42.016Å b: 42.016Å c: 81.656Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.258 0.258 0.301
Expression system: Not provided

Quick links

Citations

4 review citations

Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders.
Cleary et al. (2014)
3 more

3 mentions without citation

Structural studies of CNG repeats.
Kiliszek et al. (2014)
2 more