Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- SH2 domain
- SH2 domain superfamily
- STAT3, SH2 domain
- STAT transcription factor, DNA-binding
- STAT transcription factor, DNA-binding, N-terminal
- p53-like transcription factor, DNA-binding domain superfamily
- STAT transcription factor, all-alpha domain
- STAT transcription factor, coiled coil
1 more domain
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-117383 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Signal transducer and activator of transcription 3
Molecule details ›
Chain: A
Length: 596 amino acids
Theoretical weight: 68.14 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 596 amino acids
Theoretical weight: 68.14 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P42227 (Residues: 127-715; Coverage: 77%)
Sequence domains:
- STAT protein, all-alpha domain
- STAT protein, DNA binding domain
- Signal transducer and activator of transcription, linker domain
- SH2 domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I04-1
Spacegroup:
I41
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
