Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Interleukin-18 and 14L protein (preferred)
PDBe Complex ID:
PDB-CPX-171919 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14L protein
Molecule details ›
Chains: A, C
Length: 118 amino acids
Theoretical weight: 14 KDa
Source organism: Yaba-like disease virus
Expression system: Escherichia coli
UniProt:
Structure domains: Immunoglobulins
Length: 118 amino acids
Theoretical weight: 14 KDa
Source organism: Yaba-like disease virus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9DHU8 (Residues: 20-136; Coverage: 86%)
Structure domains: Immunoglobulins
Interleukin-18
Molecule details ›
Chains: B, D
Length: 157 amino acids
Theoretical weight: 17.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Length: 157 amino acids
Theoretical weight: 17.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q14116 (Residues: 37-193; Coverage: 81%)
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P21
Expression system: Escherichia coli
