› 4eog

X-ray diffraction
2.3Å resolution

Crystal structure of Csx1 of Pyrococcus furiosus

Released:
DOI: 10.2210/pdb4eog/pdb
PDB entry 4eog coloured by chain, front view.
PDB entry 4eog coloured by chain, side view.
PDB entry 4eog coloured by chain, top view.
Source organism: Pyrococcus furiosus DSM 3638
Primary publication:
Crystal structure and nucleic acid-binding activity of the CRISPR-associated protein Csx1 of Pyrococcus furiosus.
Kim YK, Kim YG, Oh BH
Proteins 81 261-70 (2013)
PMID: 22987782

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-164437 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative uncharacterized protein Chain: A
Molecule details ›
Chain: A
Length: 480 amino acids
Theoretical weight: 56.67 KDa
Source organism: Pyrococcus furiosus DSM 3638
Expression system: Escherichia coli
Structure domains: SSO1389-like

Ligands and Environments

2 bound ligands:
Ligand ZN 3 x ZN
Ligand SO4 1 x SO4
1 modified residue:
Ligand MSE 7 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2221
Unit cell:
a: 51.82Å b: 179.53Å c: 110.59Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.227 0.25
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Adaptation in CRISPR-Cas Systems.
Sternberg et al. (2016)
6 more

9 mentions without citation

Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing.
Anantharaman et al. (2013)
8 more