› 4eq9

X-ray diffraction
1.4Å resolution

1.4 Angstrom Crystal Structure of ABC Transporter Glutathione-Binding Protein GshT from Streptococcus pneumoniae strain Canada MDR_19A in Complex with Glutathione

Released:
DOI: 10.2210/pdb4eq9/pdb
PDB entry 4eq9 coloured by chain, front view.
PDB entry 4eq9 coloured by chain, side view.
PDB entry 4eq9 coloured by chain, top view.
Source organism: Streptococcus pneumoniae str. Canada MDR_19A
Entry authors: Minasov G, Wawrzak Z, Stogios PJ, Light SH, Kudritska M, Yim V, Savchenko A, Anderson WF, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184171 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute-binding protein family 3/N-terminal domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 27.73 KDa
Source organism: Streptococcus pneumoniae str. Canada MDR_19A
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8DRG2 (Residues: 34-276; Coverage: 96%)
Gene names: ABC-SBP, spr0146
Sequence domains: Bacterial extracellular solute-binding proteins, family 3
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

1 bound ligand:
Ligand GSH 1 x GSH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P21
Unit cell:
a: 41.801Å b: 42.391Å c: 74.248Å
α: 90° β: 94.7° γ: 90°
R-values:
R R work R free
0.169 0.168 0.19
Expression system: Escherichia coli

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