› 4eqq

X-ray diffraction
2.05Å resolution

Structure of Ltp, a superinfection exclusion protein from the Streptococcus thermophilus temperate phage TP-J34

Released:
DOI: 10.2210/pdb4eqq/pdb
PDB entry 4eqq coloured by chain, front view.
PDB entry 4eqq coloured by chain, side view.
PDB entry 4eqq coloured by chain, top view.
Source organism: Streptococcus phage TP-J34
Primary publication:
X-ray structure of a superinfection exclusion lipoprotein from phage TP-J34 and identification of the tape measure protein as its target.
Bebeacua C, Lorenzo Fajardo JC, Blangy S, Spinelli S, Bollmann S, Neve H, Cambillau C, Heller KJ
Mol Microbiol 89 152-65 (2013)
PMID: 23692331

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129230 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative host cell surface-exposed lipoprotein Ltp-like HTH region domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 107 amino acids
Theoretical weight: 12.07 KDa
Source organism: Streptococcus phage TP-J34
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O48388 (Residues: 44-142; Coverage: 70%)
Gene name: ltp
Sequence domains: Host cell surface-exposed lipoprotein
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

2 bound ligands:
Ligand SO4 6 x SO4
Ligand PO4 6 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P41212
Unit cell:
a: 82.77Å b: 82.77Å c: 100.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.164 0.163 0.179
Expression system: Escherichia coli BL21

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Citations

7 review citations

Evolutionary Ecology of Prokaryotic Immune Mechanisms.
van Houte et al. (2016)
6 more