› 4ert

X-ray diffraction
1.95Å resolution

Crystal structure of rabbit ryanodine receptor 1 (2734-2940)

Released:
DOI: 10.2210/pdb4ert/pdb
PDB entry 4ert coloured by chain, front view.
PDB entry 4ert coloured by chain, side view.
PDB entry 4ert coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Yuchi Z, Lau K, Van Petegem F
Structure 20 1201-11 (2012)
PMID: 22705209

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145900 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ryanodine receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 210 amino acids
Theoretical weight: 24.66 KDa
Source organism: Oryctolagus cuniculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P11716 (Residues: 2734-2940; Coverage: 4%)
Gene name: RYR1
Sequence domains: RyR domain
Structure domains: Globin-like

Ligands and Environments

2 bound ligands:
Ligand GOL 2 x GOL
Ligand K 1 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P21212
Unit cell:
a: 56.78Å b: 115.89Å c: 32.21Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.19 0.225
Expression system: Escherichia coli

Quick links

Citations

27 review citations

Ryanodine receptors: structure and function.
Van Petegem F. (2012)
26 more

6 mentions without citation

Cryo-electron microscopy and X-ray crystallography: complementary approaches to structural biology and drug discovery.
Vénien-Bryan et al. (2017)
5 more