Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Protein Wnt-8 and Frizzled-8 (preferred)
PDBe Complex ID:
PDB-CPX-151160 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Frizzled-8
Molecule details ›
Chain: A
Length: 132 amino acids
Theoretical weight: 15.06 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: Fz domain
Structure domains: Frizzled cysteine-rich domain
Length: 132 amino acids
Theoretical weight: 15.06 KDa
Source organism: Mus musculus
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
Q61091 (Residues: 28-150; Coverage: 19%)
Sequence domains: Fz domain
Structure domains: Frizzled cysteine-rich domain
Protein Wnt-8
Molecule details ›
Chain: B
Length: 316 amino acids
Theoretical weight: 35.19 KDa
Source organism: Xenopus laevis
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: wnt family
Structure domains: Endo-n-acetylneuraminidase fold
Length: 316 amino acids
Theoretical weight: 35.19 KDa
Source organism: Xenopus laevis
Expression system: Drosophila melanogaster
UniProt:
- Canonical: P28026 (Residues: 23-338; Coverage: 94%)
Sequence domains: wnt family
Structure domains: Endo-n-acetylneuraminidase fold
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL11-1
Spacegroup:
P41
Expression system: Drosophila melanogaster
